Plasmodium falciparum dihydroorotate dehydrogenase C276F mutant bound with triazolopyrimidine-based inhibitor DSM1
收藏Protein Data Bank Japan2023-10-11 更新2026-03-21 收录
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Plasmodium falciparum dihydroorotate dehydrogenase C276F mutant bound with triazolopyrimidine-based inhibitor DSM1 Descriptor: 5-methyl-7-(naphthalen-2-ylamino)-1H-[1,2,4]triazolo[1,5-a]pyrimidine-3,8-diium, Dihydroorotate dehydrogenase (quinone), mitochondrial, ... Authors: Tomchick, D.R, Phillips, M.A, Deng, X. Deposit date: 2018-07-06 Release date: 2018-11-14 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.099 Å) Cite: Identification and Mechanistic Understanding of Dihydroorotate Dehydrogenase Point Mutations in Plasmodium falciparum that Confer in Vitro Resistance to the Clinical Candidate DSM265. ACS Infect Dis, 5, 2019
创建时间：
2018-07-06
