Effect of Pms2 on instability in somatic tissues.

*P values indicate statistical significance between +/+ and −/−. P values are not indicated when not significant.∧Because multiple progenitor alleles were present, changes between progenitors could not be definitively identified as contractions or expansions. Contractions and expansions were conservatively defined as molecules that were at least 5% shorter than the smallest progenitor or 5% longer than the largest progenitor, respectively. Contractions, expansions, and changes between progenitors were included in “Total Mutations”.