Number of genes differentially expressed in HIV-1Tg rats and affected by nicotine.

Number of genes with significant expression differences between saline-treated HIV-1Tg rats (HIV_Sal) and F344 rats (F344 _Sal) (Row A). Some of these genes were further altered by nicotine treatment in HIV-1 Tg rats (Row B), with most restored by nicotine treatment (Row C); only two genes had their expression worsened by nicotine (Row D) in the prefrontal cortex (PFC), dorsal hippocampus (HIP), or dorsal striatum (STR) of HIV-1Tg rats.