Binding constants and antiviral response of wild-type IFNα2 and its mutants.
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https://figshare.com/articles/dataset/_Binding_constants_and_antiviral_response_of_wild_type_IFN_945_2_and_its_mutants_/1478364
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ka, kd, and KD values were determined using the XPR36 from measurements of six different protein concentrations as shown in Fig 1, with the extracellular domain of IFNAR2 being the ligand. The fraction amplitude (Amp) of antiviral response (see Fig 2) and the errors (in parenthesis) were calculated from the IFN AV dose-response curves. EC50 values are calculated from In situ measurements of 125I labelled IFNs binding to the cell surface. Standard Error for ka values is 25%, for kd is 15% and for KD is 30%.
Binding constants and antiviral response of wild-type IFNα2 and its mutants.
创建时间：
2015-07-09
