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Additional file 8 of Imipramine and olanzapine block apoE4-catalyzed polymerization of Aβ and show evidence of improving Alzheimer’s disease cognition

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Figshare2022-06-30 更新2026-04-08 收录
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https://springernature.figshare.com/articles/dataset/Additional_file_8_of_Imipramine_and_olanzapine_block_apoE4-catalyzed_polymerization_of_A_and_show_evidence_of_improving_Alzheimer_s_disease_cognition/20193618/1
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Additional file 8. Exploratory drug screen results. (A) Detailed information about the 134 hit compounds identified in the exploratory screen. (B) BBB permeability for the 134 hit compounds identified in the exploratory screen, as determined by a literature search. Positive BBB qualities were found for 87 compounds (labeled in green), negative BBB qualities were found for 41 compounds (labeled in red), and no information was found for 6 compounds (labeled in yellow).
提供机构:
Johnson, Noah R.; Viltz, Lisa; Dhanasekaran, A. Ranjitha; Markham, Neil; Chial, Heidi J.; Lucero, Esteban; Potter, Huntington; Wang, Athena C.-J.; Coughlan, Christina; Allen, Cody; Sillau, Stefan
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2022-06-30
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