Characteristics of MESA Whites and IVUS participants, by rs11574 genotype.

Data are presented as n (%) for binary measures or median [IQR] for continuous measure. “Ancestral allele” and “Risk allele carriers” refer to rs11574 genotypes. “Ancestral allele” denotes homozygote for the common allele (CC) and risk allele carrier indicates heterozygote (CT) or homozygote for the less frequent allele (TT). For MESA, rs11574 was imputed, so we use genotype dosage (i.e. the estimated number of copies of the risk allele) to classify individuals as ancestral allele (dosage in [0, 0.5)) vs. risk allele carriers (dosage in [0.5, 2]).*Summary statistics are reported for the subset of individuals with data available for at least one of the subclinical atherosclerosis phenotypes.†In MESA, data are available for “any lipid lowering medication”. For CAVA, these data represent statin use.