The European Genome-phenome Archive

The European Genome-phenome Archive (EGA) is designed to be a repository for all types of sequence and genotype experiments, including case-control, population, and family studies. We will include SNP and CNV genotypes from array based methods and genotyping done with re-sequencing methods. The EGA will serve as a permanent archive that will archive several levels of data including the raw data (which could, for example, be re-analysed in the future by other algorithms) as well as the genotype calls provided by the submitters. We are developing data mining and access tools for the database. For controlled access data, the EGA will provide the necessary security required to control access, and maintain patient confidentiality, while providing access to those researchers and clinicians authorised to view the data. In all cases, data access decisions will be made by the appropriate data access-granting organisation (DAO) and not by the EGA. The DAO will normally be the same organisation that approved and monitored the initial study protocol or a designate of this approving organisation. The European Genome-phenome Archive (EGA) allows you to explore datasets from genomic studies, provided by a range of data providers. Access to datasets must be approved by the specified Data Access Committee (DAC).

欧洲基因组-表型档案（EGA）旨在成为各类序列和基因型实验的存储库，包括病例对照、人群和家族研究。我们将包括基于阵列方法的SNP和CNV基因型以及通过重测序方法进行的基因分型。EGA将作为一个永久性档案，存储多个层次的数据，包括原始数据（例如，未来可能由其他算法进行重新分析）以及由提交者提供的基因型调用。我们正在开发数据库的数据挖掘和访问工具。对于受控访问数据，EGA将提供控制访问所需的安全措施，同时维护患者隐私，并向有权查看数据的授权研究人员和临床医生提供访问权限。在所有情况下，数据访问决策将由适当的数据访问授权组织（DAO）而非EGA作出。DAO通常是批准并监督初始研究方案的组织或该批准组织的指定代表。欧洲基因组-表型档案（EGA）允许您探索来自不同数据提供者的基因组研究数据集，但访问这些数据集必须获得指定的数据访问委员会（DAC）的批准。