Genome-wide co-occupancy of Hoxa9 and C/EBPα in Hoxa9/Meis1 transformed HSCs [ChIP-seq]

ChEBI2014-06-11 更新2026-07-21 收录

造血干细胞表观遗传

转录因子共占据分析

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-58361 数据链接链接失效反馈

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资源简介：

Genome-wide co-occupancy of Hoxa9 and C/EBPα in Hoxa9/Meis1 transformed HSCs [ChIP-seq]

创建时间：

2014-06-11

DNMT3A and TET2 Compete and Cooperate to Repress Differentiation Lineage-Specific Factors in Hematopoietic Stem Cells. Mus musculus

造血干细胞表观遗传

白血病发病机制

Mutations in the epigenetic modifiers DNMT3A and TET2 non-randomly co-occur in lymphoma and leukemia despite their epistasis in the methylation-hydroxymethylation pathway. Using double knock-out (DKO)

NIAID Data Ecosystem120

The transition from quiescent to activated states in human hematopoietic stem cells is governed by dynamic 3D genome reorganization [Low-C]

造血干细胞表观遗传

三维基因组重组

Life-long blood production requires long-term hematopoietic stem cells (LT-HSC) - marked by stemness states involving quiescence and self-renewal - to transition into activated short-term HSC (ST-HSC)

NIAID Data Ecosystem40

Expression data from Bone marrow and Fetal liver Lineage-c-Kit+Sca-1+ (LSK) cells

造血干细胞表观遗传

Ezh2基因功能

Loss of polycomb-group gene Ezh2 causes activation of fetal gene signature in adult mouse bone marrow (BM) hematopoietic stem and progenitor cells (HSPCs). Ezh2 directly represses fetal-specific let-7

NIAID Data Ecosystem30

Define roles of JMJD1B in mediating histone demethylation and gene expression

组蛋白甲基化功能

造血干细胞表观遗传

The arginine or lysine methylation status of histones dynamically changes during many essential cellular processes, particularly during embryonic and hematopoietic stem cell development. The enzymes d

NIAID Data Ecosystem50

Stella regulates the development of female germline stem cells by modulating chromatin structure and DNA methylation [Hi-C]

造血干细胞表观遗传

三维基因组学

We use in situ Hi-C to report the most comprehensive survey to date of chromatin organization in female germline stem cells Overall design: Examination of the chromatin architecture in female germline

NIAID Data Ecosystem30

Genome-wide co-occupancy of Hoxa9 and C/EBPα in Hoxa9/Meis1 transformed HSCs [ChIP-seq]

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