Zfp322a regulates mouse ES cell pluripotency and enhances reprogramming efficiency

ChEBI2013-10-31 更新2026-07-21 收录

干细胞多能性调控

体细胞重编程优化

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-45140 数据链接链接失效反馈

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Zfp322a regulates mouse ES cell pluripotency and enhances reprogramming efficiency

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2013-10-31

PCGF6, a polycomb group protein, regulates mesodermal lineage differentiation in murine ES cells and functions in iPS reprogramming. Mus musculus

干细胞多能性调控

iPSC重编程

Polycomb group (PcG) proteins comprise a large group of evolutionary conserved factors with essential roles for embryonic development and adult stem cell function. PcG proteins constitute two main mul

NIAID Data Ecosystem140

LncPRESS1 is a p53-regulated lncRNA that safeguards pluripotency by disrupting SIRT6 mediated de-acetylation of histone H3K56

干细胞多能性调控

表观遗传修饰

Recent evidence suggests that lncRNAs play an integral regulatory role in numerous functions, including determination of cellular identity. We determined global expression (RNA-seq) and genome wide pr

NIAID Data Ecosystem30

PRAMEL7 and CUL2 decrease NuRD stability to establish ground-state pluripotency

干细胞多能性调控

染色质复合体降解

Pluripotency is established in E4.5 preimplantation epiblast. Embryonic stem cells (ESCs) represent the immortalization of pluripotency, however, their gene expression signature only partially resembl

NIAID Data Ecosystem20

Global gene expression of SLC35F2 Knock-out (KO) H9 with control hESCs

干细胞多能性调控

基因敲除转录组

Analysis of SLC35F2 KO hESCs compared with control hESCs. In order to investigate whether SLC35F2 KO affect pluripotency in hESCs, we performed RNA-Seq with SLC35F2 KO and control H9 cells. After esta

NIAID Data Ecosystem110

Investigating the role of NODAL signalling in preimplantation human embryos

胚胎发育分子机制

干细胞多能性调控

NODAL signalling is required to maintain pluripotency in human embryonic stem cells, by maintaining expression of transcription factor NANOG. We treated human blastocysts with NODAL signalling inhibit

NIAID Data Ecosystem30

Zfp322a regulates mouse ES cell pluripotency and enhances reprogramming efficiency

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