BindingDB Entry 50039816: Discovery of GNF-5837, a Selective TRK Inhibitor with Efficacy in Rodent Cancer Tumor Models.

Small molecule binding data for protein ALK tyrosine kinase receptor, Cytoplasmic tyrosine-protein kinase BMX, Ephrin type-A receptor 3, Ephrin type-B receptor 2, Fibroblast growth factor receptor, Insulin receptor, Insulin-like growth factor 1 receptor, JNK1/JNK2, Macrophage colony-stimulating factor 1 receptor (c-Fms), Macrophage-stimulating protein receptor, Mast/stem cell growth factor receptor Kit, NT-3 growth factor receptor, Neuronal proto-oncogene tyrosine-protein kinase Src, Neurotrophic tyrosine kinase receptor, Neurotrophic tyrosine kinase receptor type 2, Platelet-derived growth factor receptor, Proto-oncogene tyrosine-protein kinase ROS, Proto-oncogene tyrosine-protein kinase receptor Ret, Receptor-type tyrosine-protein kinase FLT3, TPR/MET fusion protein, Tyrosine-protein kinase Fgr, Tyrosine-protein kinase Kit (Kit), Tyrosine-protein kinase Lyn, Tyrosine-protein kinase ZAP-70, Tyrosine-protein kinase receptor Tie-1, and Vascular endothelial growth factor receptor 1, Uniprot P04629, P05480, P05532, P05622, P09581, P10721, P14234, P15208, P16056, P25911, P29319, P35546, P35969, P43404, P54763, P97504, P97793, Q00342, Q03142, Q06806, Q16288, Q16620, Q60751, Q61851, Q62190, Q78DX7, and Q9WTU6