Comprehensive identification and characterization of the binding sites of HIF-1alpha in mammalian genes were attempted. We used ChIP-Seq method, in which next gene sequencing technology and chromatin-
Motif discovery is essential for deciphering regulatory codes from high throughput genomic data, such as those from ChIP-chip/seq experiments. However, there remains a lack of effective and efficient
The histone variant H2A.Z is central to early embryonic development, determining transcriptional competency through chromatin regulation of gene promoters and enhancers. In addition to genic loci, we