Expression data of mRNA from normal utricle and vestibular flat epithelium of adult mice

The vestibular sensory epithelium may degenerate into a layer of flat cells, known as flat epithelium, after a severe lesion, but the pathogenesis of vestibular flat epithelium remains unclear. We used microarrays to detail the global programme of gene expression in normal utricle and vestibular flat epithelium and identified whether epithelial-mesenchymal transition participite in this process High dose of streptomycin was inoculated into the inner ear through the posterior semicircular canal to induce a severe lesion in the adult mouse utricle, normal utricle and vestibular flat epithelium samples were collected for RNA extraction and hybridization on Affymetrix mRNA arrays.