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Identification of EP4 as a Potential Target for the Treatment of Castration-Resistant Prostate Cancer Using a Novel Xenograft Model

ChEBI2010-06-08 更新2026-07-21 收录

去势抵抗性前列腺癌靶点发现

异种移植模型分析

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-21887 数据链接链接失效反馈

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Identification of EP4 as a Potential Target for the Treatment of Castration-Resistant Prostate Cancer Using a Novel Xenograft Model

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创建时间：

2010-06-08

前列腺癌转录组学

异种移植模型分析

Purpose: Validate the cell type specific (Epithelial, Endothelial, and Stromal) transcriptome profile between prostate primary tissue xenografts and of fresh prostate tissue. Nude-Fox1nu mice were ca

NIAID Data Ecosystem80

Transcriptome analysis of xenograft tumors treated with vehicle control or CBL0137. Transcriptome analysis of xenograft tumors treated with vehicle control or CBL0137

癌症药物转录组学

异种移植模型分析

RNAseq was used to identify host and viral transcriptome changes in xenograft tumors treated with DMSO or CBL0137. Mouse xenograft experiments were regulated by Institutional Animal Care & Use Committ

NIAID Data Ecosystem30

Comprehensive genomics in androgen receptor-dependent castration-resistant prostate cancer using a patient-derived xenograft and cell lines

激素受体信号通路

去势抵抗性前列腺癌靶点发现

Castration resistance is a lethal form of treatment failure of prostate cancer (PCa) and is associated with activation of the androgen receptor (AR). It is only partially understood how the AR mediate

NIAID Data Ecosystem20

Simultaneous analysis of tumor and stromal gene expression profiles from xenograft models. Simultaneous analysis of tumor and stromal gene expression profiles from xenograft models

微环境基因表达

异种移植模型分析

Identifying the gene expression alterations that occur in both the tumor and stroma is essential to understanding tumor biology. We have developed a dual-species microarray analysis method that allows

NIAID Data Ecosystem50

mRNA-seq analysis of oral squamous cell carcinoma (OSCC) cell line OC3 and TW2.6 derived xenografts (CDXs)

肿瘤微环境转录组

异种移植模型分析

In many solid tumors, tissue of mesenchymal subtype is frequently associated with epithelial-mesenchymal transition (EMT) state, strong stromal infiltration, and poor prognosis. Emerging evidence from

NIAID Data Ecosystem30

Identification of EP4 as a Potential Target for the Treatment of Castration-Resistant Prostate Cancer Using a Novel Xenograft Model

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