Studies of T cell activation by IL-2 variants

NIAID Data Ecosystem2026-05-01 收录

T细胞激活

IL-2变体免疫调节

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP485979 数据链接链接失效反馈

官方服务：

资源简介：

This study to confirm the differences of T cell activation by wtIL-2 or by IL-2 variant 012.

创建时间：

2024-04-03

Expression data from unactivated vs. activated PBMCs

T细胞激活

离子通道表达

Long-lasting activation of T cells requires up-regulation of many genes, for example of transcription factors, cytoskeletal proteins and cell surface proteins encluding ion channels. An increase of io

NIAID Data Ecosystem70

DNase-seq from activated T-cell (ENCSR038POV)

染色质可及性

T细胞激活

For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODE_Data_Use_Policy_for_External_Users_03-07-14.pdf https://www.e

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Effects of PP2Ac over-expression on mouse naïve CD4 T cell gene profile upon activation. Mus musculus

T细胞激活

基因表达调控

A transgenic mouse was generated using a CD2-driven transgene containing the cDNA of Ppp2ca to achieve over-expression of PP2Ac in T cells. Naïve CD4 T cells were isolated and lysed at times 0, 6, and

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Dynamic changes in tRNA modifications and abundance during T-cell activation

tRNA修饰动态变化

T细胞激活

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

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DNase-seq from activated T-cell (ENCSR312INU)

染色质可及性

T细胞激活

NIAID Data Ecosystem50