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Deep Sequencing the microRNA profile in rhabdomyosarcoma reveals down-regulation of miR-378 family members

ChEBI2015-01-28 更新2026-07-21 收录

横纹肌肉瘤

microRNA表达谱分析

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-3246 数据链接链接失效反馈

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资源简介：

Deep Sequencing the microRNA profile in rhabdomyosarcoma reveals down-regulation of miR-378 family members

应用场景：

创建时间：

2015-01-28

横纹肌肉瘤

信号通路抑制

Rhabdomyosarcoma (RMS) is the most common pediatric soft tissue sarcoma with poor prognosis. RMS frequently show Hedgehog (HH) pathway activity, which is predominantly seen in the embryonal subtype (E

NIAID Data Ecosystem90

KDM3B inhibitors disrupt PAX3-FOXO1 oncogenic activity in fusion positive rhabdomyosarcoma.. KDM3B inhibitors disrupt PAX3-FOXO1 oncogenic activity in fusion positive rhabdomyosarcoma.

横纹肌肉瘤

KDM3B抑制剂筛选

Fusion-positive alveolar rhabdomyosarcoma (FP-RMS) is an aggressive pediatric sarcoma driven primarily by the PAX3-FOXO1 fusion oncogene, for which therapies targeting PAX3-FOXO1 are lacking. We scree

NIAID Data Ecosystem30

The effect of SNAIL transcription factor on microRNA transcriptome in rhabdomyosarcoma

转录因子调控

横纹肌肉瘤

The main goal of the project was to analyze the effect of SNAIL transcription factor on microRNA expression profile in rhabdomyosarcoma (RMS) cells using the next generation sequencing. Differential e

NIAID Data Ecosystem20

Affymetrix SNP array data for pediatric rhabdomyosarcoma (RMS). Homo sapiens

横纹肌肉瘤

拷贝数变异分析

To elucidate the pathogenesis of rhabdomyosarcoma (RMS), particularly for different subgroups, we performed a SNP array-based copy number analysis of 54 RMS specimens from primary cases with ERMS (N =

NIAID Data Ecosystem60

Expression profiling of NRAS knockout in embryonal rhabdomyosarcoma (ERMS) cells. Expression profiling of NRAS knockout in embryonal rhabdomyosarcoma (ERMS) cells

横纹肌肉瘤

NRAS基因功能

Targeted disruption of NRAS was performed in a stable 381T ERMS cell line harboring tamoxifen inducible CRISPR/Cas9 gRNA against NRAS Overall design: RNA sequencing was performed using RNA extracted f

NIAID Data Ecosystem30

Deep Sequencing the microRNA profile in rhabdomyosarcoma reveals down-regulation of miR-378 family members

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