File S1 - Reactive Oxygen Species Production and Mitochondrial Dysfunction in White Blood Cells Are Not Valid Biomarkers of Ageing in the Very Old

File S1 includes the following: Figure S1. Quantification of superoxide levels, mitochondrial mass and mitochondrial membrane potential in PBMCs and cell subpopulations by flow cytometry. Figure S2. Short term intra-individual stability and day-day precision of superoxide levels, mitochondrial mass and mitochondrial membrane potential. Figure S3. Scatter plots of agreements between superoxide levels, mitochondrial mass and mitochondrial membrane potential. Figure S4. Scatter plots of superoxide levels, mitochondrial mass and mitochondrial membrane potential in relation to other potential markers of oxidative stress-induced cellular senescence. Figure S5. Scatter plots of superoxide levels, mitochondrial mass and mitochondrial membrane potential in relation to other potential markers of oxidative stress-induced cellular senescence after removal of extreme outliers. Figure S6. Scatter plots of superoxide levels, mitochondrial mass and mitochondrial membrane potential in relation to informative BoA. Figure S7. Scatter plots of superoxide levels, mitochondrial mass and mitochondrial membrane potential in relation to informative BoA after removal of extreme outliers. Table S1. Stability of superoxide levels, mitochondrial mass and mitochondrial membrane potential in PBMCs during various experimental handling. Table S2. Agreements between superoxide levels, mitochondrial mass and mitochondrial membrane potential. Table S3. Agreements between superoxide levels, mitochondrial mass and mitochondrial membrane potential after removal of extreme outliers. Table S4. Superoxide levels, mitochondrial mass and mitochondrial membrane potential in relation to other potential markers of oxidative stress-induced cellular senescence after removal of extreme outliers. Table S5. Superoxide levels, mitochondrial mass and mitochondrial membrane potential in relation to informative BoA after removal of extreme outliers. Table S6. Association between superoxide levels, mitochondrial mass and mitochondrial membrane potential and age-related outcomes after removal of extreme outliers. Supplementary Methods. (DOCX)