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Adaptive evolution of Streptomyces albulus

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA1204052
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Adopting a low pH adaptive evolution strategy that gradually increases selection pressure, after 93 consecutive days of adaptive evolution, the tolerance pH value of the albulus GS114 decreased from 4.0 to 3.6. After extensive screening, the low pH adaptive evolutionary strain S. was obtained albulus ALE4.0, S. albulus ALE3.8, and S. albulus ALE3.6; Combining low pH tolerance and shake flask fermentation experiments, the optimal adaptive evolutionary strain was determined to be S. albulus ALE3.6. And resequencing comparison was conducted.
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2024-12-29
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