Effects of H3.3G34V Mutation on Genomic H3K36 and H3K27 Methylation Patterns in Isogenic Pediatric Glioma Cell Lines

This project aims to investigate the effect of histone H3G34V on H3K36me3 and H3K27me3 enrichment. Here are the raw ChIP-Seq data for KNS42 WT (unmodified), KNS42 transduced with DOX-inducible shRNA targeting H3F3A no DOX control, and KNS42 transduced with DOX-inducible shRNA targeting H3F3A +DOX.

本项研究旨在探讨组蛋白H3G34V对H3K36me3和H3K27me3富集的影响。以下为KNS42野生型（未修饰）、经DOX诱导型shRNA转导靶向H3F3A的KNS42细胞未添加DOX的原始ChIP-Seq数据，以及经DOX诱导型shRNA转导靶向H3F3A并添加DOX的KNS42细胞的原始ChIP-Seq数据。