Lipid loci with multiple signals in Europeans.

aLD (r2/D′) with SNP showing the strongest evidence of association at each locus. bβ: effect size from an additive model and corresponding to the effect allele, in the unit of mmol/L for HDL-C, LDL-C and natural log transformed TG. cP values of sequential conditional analyses, in which we added the SNP with the strongest evidence of association into the regression model as a covariate and tested for the next strongest SNP until the strongest SNP showed a conditional P value>10−4 and had no annotation suggesting potential function. dVariance explained by SNPs at each locus was estimated based on European samples. eP values of initial association in African Americans and East Asians.