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Crystal structure of FGFR3 in complex with pyrimidine derivative

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Protein Data Bank Japan2024-11-20 更新2026-03-21 收录
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Crystal structure of FGFR3 in complex with pyrimidine derivative Descriptor: 2-[[5-[2-(3,5-dimethoxyphenyl)ethyl]-2-[[3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]amino]pyrimidin-4-yl]amino]-N-ethyl-benzenesulfonamide, Fibroblast growth factor receptor 3 Authors: Echizen, Y, Tateishi, Y, Amano, Y. Deposit date: 2020-02-04 Release date: 2020-04-08 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.53 Å) Cite: Structure-based drug design of 1,3,5-triazine and pyrimidine derivatives as novel FGFR3 inhibitors with high selectivity over VEGFR2. Bioorg.Med.Chem., 28, 2020
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2020-02-04
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