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Reactivity of Mitsunobu Reagent toward Carbonyl Compounds

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NIAID Data Ecosystem2026-03-06 收录
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The nitrogen-based nucleophile generated from azodicarboxylate and triphenylphosphine displayed an excellent reactivity toward carbonyl compounds to generate a variety of different final products depending on the substituent pattern on the carbonyl carbon. From the structures of these adducts, a straightforward mechanistic interpretation for the formation of different products is provided.

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2016-05-06
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