Analysis of VOCs production-emission characteristics from chemical medicine preparation manufacturing industry in Beijing

Analyzing the production-emission characteristics of volatile organic compounds （VOCs） in key industries is the basis for promoting the green upgrading of the industry and winning the Battle Against Air pollution. This study conducted an investigation and research on the sub-industry of chemical medicine preparation manufacturing in the pharmaceutical manufacturing industry in Beijing. Taking VOCs production-emission as the main line， the whole chain of the production process， VOCs-related raw and auxiliary materials， and VOCs waste gas collection and treatment were investigated and sorted out. The production volume， emission， and production-emission coefficient of VOCs in the sub-industry were studied and calculated. The results showed that the process units producing VOCs in the chemical medicine preparation manufacturing industry were concentrated in the wet granulation， drying， and coating process units of solid preparations， and the dissolution/concentration， filling， and lyophilization process units of liquid preparations. The amount of VOCs raw and auxiliary materials used in the chemical medicine preparation manufacturing industry in Beijing was approximately 1500 tons. The types of VOCs raw and auxiliary materials were mainly ethanol， isopropyl alcohol， and acetone. The amount of VOCs raw and auxiliary materials used in the coating process unit was the largest， accounting for 30.48%. The end treatment of VOCs was mostly by a single activated carbon adsorption method， accounting for 67.1%. Based on product output，output value， and the number of enterprises，VOCs production coefficients for the chemical medicine preparation manufacturing industry were 30.40 tons/ten thousand tons， 2.56 tons/hundred million yuan， and 8.43 tons per enterprise， respectively. Through the material balance calculation， VOCs emission coefficients were 23.75 tons/ten thousand tons， 2.00 tons/hundred million yuan， and 6.59 tons per enterprise， respectively. The study comprehensively analyzed the characteristics and coefficients of VOCs production and emission in the chemical medicine preparation manufacturing industry. It can provide theoretical support for the pollution prevention and fine control of VOCs in the pharmaceutical manufacturing industry in Beijing.