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Proteomic analysis of ARPE-19 cells exposed to chronic H2O2 treatment

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https://www.omicsdi.org/dataset/pride/PXD022545
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We performed a proteomic analysis of a retinal pigment epithelium cell line (ARPE-19) exposed to long-term sublethal levels of H2O2 to mimic low-level pro-oxidative insult in age-related macular degeneration (AMD). using a wide range of biochemical analyses and cell culture techniques, we highlighted changes in energy metabolism, extracellular matrix organization and inflammation-related processes, which may help in understanding the molecular pathogenesis of AMD.
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2021-01-04
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