Simultaneous targeting linked loci in mouse embryos using base editing
收藏NIAID Data Ecosystem2026-03-10 收录
下载链接：
https://www.ncbi.nlm.nih.gov/bioproject/PRJNA489707
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资源简介：
Base editing covers an exceptional range of applications, both in basic and applied sciences. Through the co-injection of two base editors and two sgRNAs into mouse zygotes, we introduced C•G-to-T•A transitions into two putative cytokine-sensing transcription enhancers separated by 9kb. Whole genome sequences (WGS) was conducted to investigate possible off-target mutations on predicted off-target sites.
创建时间：
2018-09-06
