Crystal structure of Human HPSE1 in complex with inhibitor
收藏Protein Data Bank Japan2024-10-23 更新2026-03-28 收录
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Crystal structure of Human HPSE1 in complex with inhibitor Descriptor: (5~{S},6~{R},7~{S},8~{S})-6,7,8-tris(oxidanyl)-2-[2-[4-(trifluoromethyl)phenyl]ethyl]-5,6,7,8-tetrahydroimidazo[1,2-a]pyridine-5-carboxylic acid, Heparanase 50 kDa subunit, Heparanase 8 kDa subunit Authors: Mima, M, Fujimoto, N, Imai, Y. Deposit date: 2022-07-15 Release date: 2022-12-07 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Lead identification of novel tetrahydroimidazo[1,2-a]pyridine-5-carboxylic acid derivative as a potent heparanase-1 inhibitor. Bioorg.Med.Chem.Lett., 79, 2022
创建时间：
2022-07-15
