five

histone modification signatures in mice melanoma progression

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https://www.omicsdi.org/dataset/pride/PXD019313
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In the search for the biological mechanisms that underlie melanoma development, we have developed a cellular system that models tumor initiation and transformation from melanocytes to metastatic melanoma cells.. To evaluate histone PTM, we applied a workflow to globally detect histone PTM by mass spectrometry approaches allowing the interrogation of more than 40 PTMs sites and 200 PTMs combinations.
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2021-09-09
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