Synthesis of IPs in the nucleus

Within the nucleus, inositol polyphosphate multikinase (IPMK), inositol-pentakisphosphate 2-kinase (IPPK), inositol hexakisphosphate kinase 1 (IP6K1) and 2 (IP6K2) produce IP5, IP6, IP7, and IP8 inositol phosphate molecules (Irvine & Schell 2001, Alcazar-Romain & Wente 2008, York 2006, Monserrate and York 2010, Nalaskowski et al. 2002, Chang et al. 2002, Chang & Majerus 2006, Saiardi et al. 2001, Saiardi et al. 2000, Draskovic et al. 2008, Mulugu et al. 2007).

在细胞核内，肌醇多磷酸多激酶（IPMK）、肌醇五磷酸2激酶（IPPK）、肌醇六磷酸激酶1（IP6K1）及2（IP6K2）通过催化作用生成肌醇五磷酸（IP5）、肌醇六磷酸（IP6）、肌醇七磷酸（IP7）和肌醇八磷酸（IP8）等肌醇磷酸分子（参见Irvine & Schell 2001，Alcazar-Romain & Wente 2008，York 2006，Monserrate and York 2010，Nalaskowski et al. 2002，Chang et al. 2002，Chang & Majerus 2006，Saiardi et al. 2001，Saiardi et al. 2000，Draskovic et al. 2008，Mulugu et al. 2007）。