Data Accompanying: Berger, Alvarado, and Kiss (2019)
收藏Figshare2019-03-14 更新2026-04-08 收录
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https://figshare.com/articles/Data_Accompanying_Berger_Alvarado_and_Kiss_2019_/7795772/1
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Cytoplasmic capping is an understudied epitranscriptomic RNA modification that could have large ramifications on gene expression. Simply, cytoplasmic capping returns a N7-methylguanosine cap onto the 5' end of an uncapped RNA. In the paper linked to this work, we detect uncapped and truncated 5' mRNA ends in cells were cytoplasmic capping is normal in addition to cells where it has been blocked. The majority of these uncapped ends map to previously identified cap sites. Further, we show data which hint that recapping may be driven by sequences of the RNAs themselves. Together, these data support earlier studies andhint that alternative splicing may aid in selecting or targeting mRNAs for cytoplasmic capping.<br>The data posted here are supporting data (including gels and/or blots showing additional sample replicates for our experiments, additional cloned sequences information, etc) that could not be published with the paper due to page constraints and/or standard conventions (like only showing 1 replicate in a publication). <br>
提供机构:
Mikeala R. Berger
创建时间:
2019-03-14



