Additional file 4: of Stoichiometric gene-to-reaction associations enhance model-driven analysis performance: Metabolic response to chronic exposure to Aldrin in prostate cancer

GSMM readjustments/refinement process. This file includes; i) Definition of Metabolites included in the biomass reaction, ii) Required Metabolic Functionalities (RMF) necessary to apply GIMME algorithm, iii) Experimentally measured metabolites annotated in HMR2 and iv) automatically generated GPR and S-GPR of each catalytic reaction in HMR2 (algorithm in Additional file 5) (XLSX 190 kb)