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RNA SEQUENCE-SPECIFIC MEDIATORS OF RNA INTERFERENCE

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国家林业和草原科学数据中心2023-02-12 更新2024-03-07 收录
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PROBLEM TO BE SOLVED: To provide RNA sequence-specific mediators of RNA interference. SOLUTION: Disclosed herein is a double-stranded RNA in a form of two separate RNA strands not covalently linked, where respective strands of the isolated double-stranded RNA are 21-23 nucleotides in length, and one of the strands of the isolated double-stranded RNA has complete sequence complementarity to mRNA of a gene, the isolated double-stranded RNA causes cleavage of the mRNA to mediate the RNA interference of the mRNA of the gene, and the mRNA is cleaved within a region of sequence-complementarity with the isolated double-stranded RNA. SELECTED DRAWING: None
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国家林业和草原科学数据中心
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2023-02-12
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