Per case probability estimates of different diagnosis- and treatment-related outcomes for drug sensitive, multi-drug resistant and extensively-drug-resistant tuberculosis.

*These proportions were not included in the model as all MDR-TB and XDR-TB cases follow the same diagnosis and treatment protocols regardless of smear status in accordance with national guidelines. Additionally, we only modelled new cases of MDR-TB and XDR-TB and did not include retreatment cases.†Assumed that all DS-TB patients are treated at a primary care clinic and none are hospitalized.‡This estimate was provided by Brooklyn Chest Hospital.§A figure of 50% is assumed for the decentralized XDR-TB model based on a proportion of patients from an XDR-TB cohort who weigh >50 kg,¶Not incorporated into our model as we assume all DS-TB patients complete a full course of treatment, whether they are cured or they fail treatment.#Assumed to be the same as XDR-TB.DS-TB - Drug sensitive tuberculosis, MDR-TB – Multi-drug resistant tuberculosis, XDR-TB – Extensively Drug-resistant tuberculosis, PCC - primary care clinic, ADR - Adverse Drug reaction.