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CRISPRi-mediated functional analysis of lung disease-associated loci at non-coding regions [ChIP-seq]

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NIAID Data Ecosystem2026-03-11 收录
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ChIP-seq was performed to identify dCas9-KRAB binding sites in the presence of sgRNA (sgTGFB1_B9D2) targeting a region with rs1800469 between TGFB1 and B9D2 in H441 lung papillary adenocarcinoma cells. Overall design: Locations of dCas9-KRAB and its associated repressive histone mark H3K9me3 were investigated in two lines of H441 cells expressing dCas9-KRAB with or without the sgRNA.

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2020-06-09
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