Intratumoral Influenza Vaccine for Early Colorectal Cancer

Primary:To investigate if intratumoral influenza vaccine is a safe treatment modality for tumor down staging prior to intended curative surgery in patients undergoing treatment for colorectal cancer.
Primary endpoints: Safety endpointsSafety evaluation will be performed via continuous assessment of safety parameters by reviewing events as they arise. We will conduct the pilot study in order to measure potential safety issues in a small cohort of patients before including patients in the phase 2 study.The investigation will be put on hold if unacceptable safety issues are detected.Primary safety endpoints:1. Evaluation of serious adverse events2. Evaluation of any adverse events reported.