Synthetic Studies on Lactonamycins: Synthesis of the Model BCDEF Aglycon
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https://figshare.com/articles/dataset/Synthetic_Studies_on_Lactonamycins_Synthesis_of_the_Model_BCDEF_Aglycon/2740915
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资源简介：
The lactonamycin model aglycon 4 was synthesized from the trihalogenated benzene derivative 10. Ethynyltetraol 6 was prepared from 10 via carbon elongations, oxidative demethylation, a cycloaddition reaction with the diene derived from homophthalic anhydride, and dihydroxylation. Final E- and F-ring constructions from 6 were realized via a palladium-catalyzed cyclization−methoxycarbonylation, a stereoselective methanol addition, and lactonization, leading to the production of 4.
创建时间：
2010-08-20
