Microwave-Assisted Copper-Catalyzed Four-Component Tandem Synthesis of 3‑N‑Sulfonylamidine Coumarins

Microwave-assisted copper-catalyzed four-component tandem synthesis of 3-N-sulfonylamidine coumarins has been accomplished by the coupling of salicylaldehydes, propiolates, sulfonyl azides, and secondary amines. This one-pot protocol affords an effective route for the construction of functionalized coumarin structural frameworks in a single operation with moderate to high yields.