five

Optimised model outputs.

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https://figshare.com/articles/dataset/Optimised_model_outputs_/7859444
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This table displays optimised values for the critical model parameters outlined in Fig 5. Outputs are shown for the primary model (presented throughout this report) and three variant models; CD81/SR-B1 unbinding models are based on the primary model but also allow for receptor dissociation, for these models the optimised dissociation rate is given in parentheses; in the null model SR-B1 binding does not affect the rate of CD81 acquisition, in this case parameter s (annotated by asterisk) is optimised purely using the sE2 binding data. The models can also be used to predict the fate of membrane bound virus particles. Here, we provide the inferred proportion of viruses that acquire sufficient CD81, that complete downstream steps of entry and that achieve productive infection.
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2019-03-18
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