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Crystal Structure of KSP in Complex with Inhibitor 22

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Protein Data Bank Japan2024-02-21 更新2026-03-21 收录
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Crystal Structure of KSP in Complex with Inhibitor 22 Descriptor: 1-[(4R)-4-[3-(4-ACETYLPIPERAZIN-1-YL)PROPYL]-1-(2-FLUORO-5-METHYLPHENYL)-4-PHENYL-4,5-DIHYDRO-1H-PYRAZOL-3-YL]ETHANONE, ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein KIF11, ... Authors: Yan, Y. Deposit date: 2007-05-29 Release date: 2007-09-18 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (3 Å) Cite: Kinesin spindle protein (KSP) inhibitors. Part 8: Design and synthesis of 1,4-diaryl-4,5-dihydropyrazoles as potent inhibitors of the mitotic kinesin KSP. Bioorg.Med.Chem.Lett., 17, 2007
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2007-05-29
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