Processed snRNA-seq Seurat object for cortices of the MCT8-OATP1C1-deficient Allan-Herndon-Dudley Syndrome mouse model

This dataset contains a processed snRNA sequencing dataset stored as a Seurat object (.rds). The object includes normalized gene expression data, cell-level metadata, dimensionality reductions (PCA and UMAP), and cell-type annotations. Organism: Mus Musculus Tissue: cortical hemispheres and attached cerebral nucleiGroups: 3 x WT, 3x dKO (global, MCT8 & OATP1C1)Mouse Info: age of sampling at P21, pure C57BL/6J background. Animals were pooled from multiple litters to minimize litter effects. All mice were group-housed on a 12:12-h light-dark cycle at 23°C and fed standard chow diet ad libitum Technology: 10x Genomics Nuclei: 77897 Genes: 22545 Data processing was performed using Seurat (v4).