Distribution of microbial communities and core microbiome in successive wound grades of diabetic foot ulcer individuals. clinical metagenome

Diabetic foot ulcer (DFU) is a major complication of diabetes with high morbidity and mortality rates. Pathogenesis of DFUs is governed by a complex milieu of environmental and host factors. A thorough and rapid analysis of the microbial landscape is a major requirement towards devising evidence-based interventions for treatment of DFU. Towards this, wound samples were sampled for their bacterial community structure using both culture-based and next-generation 16S rRNA based metagenomics approach.