Structure of Pteridine Reductase 1 (PTR1) from Trypanosoma brucei in ternary complex with cofactor (NADP+) and inhibitor (Compound AX5)
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Structure of Pteridine Reductase 1 (PTR1) from Trypanosoma brucei in ternary complex with cofactor (NADP+) and inhibitor (Compound AX5) Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 6-(benzylsulfanyl)pyrimidine-2,4-diamine, ACETATE ION, ... Authors: Martini, V.P, Iulek, J, Hunter, W.N. Deposit date: 2007-12-13 Release date: 2008-12-16 Last modified: 2025-03-26 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structure-based design of pteridine reductase inhibitors targeting african sleeping sickness and the leishmaniases. J.Med.Chem., 53, 2010
创建时间：
2007-12-13
