Structure-Assisted Functional Anchor Implantation in Robust Metal–Organic Frameworks with Ultralarge Pores

A facile functionalization
assisted by the structural attributes
of PCN-333 has been studied while maintaining the integrity of the
parent MOF including ultralarge pores, chemical robustness, and crystallinity.
Herein we thoroughly analyzed ligand exchange phenomena in PCN-333
and demonstrate that the extent of exchange can be tailored by varying
the exchange conditions as potential applications may require. Through
this method a variety of functional groups are incorporated into PCN-333.
To further show the capabilities of this system introduction of a
BODIPY fluorophore as a secondary functionality was performed to the
functionalized framework via a click reaction. We anticipate the PCN-333
with functional anchor can serve as a stable platform for further
chemistry to be explored in future applications.