Ocular parameters of the study participants.

PurposeTo investigate the heritability of genetic influence on macular choroidal vascularity index (CVI).MethodsTotal choroidal area (TCA), luminal area (LA), and CVI was measured using horizontal scan of spectral-domain optical coherence tomography with enhanced depth imaging in the 373 healthy twin participants. Characteristics of the participants were investigated, including age, sex, axial length, hypertension, diabetes, drinking habits, and smoking status. Univariate and subsequent multivariate regression analyses were performed to evaluate the associations of these factors with TCA, LA, and CVI.ResultsPatients who were older and had a higher intraocular pressure, higher diastolic blood pressure, and lower pulse pressure showed associations with lower CVI (pConclusionThe TCA, LA, and CVI are highly heritable.