Malaria Host Pathogen Interaction Center (MaHPIC) Experiment 24 (E24) Clinical Results

Experiment 24: Macaca mulatta infected with Plasmodium cynomolgi B strain, in a homologous challenge, to produce and integrate clinical, hematological, parasitological, and omics measures of acute primary infection and relapses. This clinical results dataset contains measures of disease infection including counts and calucations for: CBCs, reticulocytes, parasitemias, and downstream immunological, functional genomic, lipidomic, and metabolomic measurements. Results also include data and metadata from veterinarians on all facets of animal access, including, but not limited to: treatments, hematology, biochemical analyses, parasitology, bacteriology, and surgery statistics, etc. Results also include documentation of data collection and analysis methods and supporting clinical matarials that differentiate between 'Idealized' and 'Actual' disease progression. This is the second in a series of experiments that includes infection of malaria-naïve subjects (Experiment 23, P. cynomolgi B strain) and heterologous challenge (Experiment 25, P. cynomolgi strain ceylonensis) for the individuals from the same cohort. Subjects were cleared of previous infection with P. cynomolgi B strain via treatment with the anti-malarial drugs artemether, chloroquine, and primaquine. Please see the file 'E24M99MEMmCyDaWB_README-PlasmoDB-09242018-V1_MULTIPL.txt for a full description of this dataset and for instructions on how to access other datasets from this experiment. Please see https://plasmodb.org/plasmo/mahpic.jsp for descriptions and locations of all public MaHPIC datasets.