Discovery of imidazoquinolines as a novel class of potent, selective and in vivo efficacious COT kinase inhibitors
收藏Protein Data Bank Japan2025-01-29 更新2026-03-21 收录
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Discovery of imidazoquinolines as a novel class of potent, selective and in vivo efficacious COT kinase inhibitors Descriptor: Mitogen-activated protein kinase kinase kinase 8, N-[2-(morpholin-4-yl)ethyl]-6-(8-phenyl-1H-imidazo[4,5-c][1,7]naphthyridin-1-yl)-1,3-benzothiazol-2-amine Authors: Gutmann, S, Hinniger, A. Deposit date: 2016-03-17 Release date: 2016-08-24 Last modified: 2025-01-29 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Discovery of Imidazoquinolines as a Novel Class of Potent, Selective, and in Vivo Efficacious Cancer Osaka Thyroid (COT) Kinase Inhibitors. J.Med.Chem., 59, 2016
创建时间：
2016-03-17
