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Single cell expression profiling of the mouse Sox17-null myocardium at E8.5

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To understand the function of Sox17 in the precursor cells of the mouse endocardium amd the effect in the developing heart tube, single cell expression profiling of the Sox17-null endocardium and myocardium were performed. 4 samples, each for Sox17 wild type and mesoderm-specific knockout myocardial cells. Each array represents a single cell.

为阐明Sox17在小鼠心内膜(endocardium)前体细胞中的功能,以及其对发育中心脏管的影响,本研究对Sox17敲除(knockout)的心内膜与心肌细胞(myocardial cells)开展了单细胞表达谱分析。实验共包含4个样本,分别为Sox17野生型(wild type)及中胚层(mesoderm)特异性敲除的心肌细胞,每个阵列对应一个单细胞。

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