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A system for genome-wide histone variant dynamics in ES cells reveals dynamic MacroH2A2 replacement at promoters

ChEBI2014-08-08 更新2026-07-21 收录

组蛋白变体

胚胎表观遗传调控

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-57665 数据链接链接失效反馈

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资源简介：

A system for genome-wide histone variant dynamics in ES cells reveals dynamic MacroH2A2 replacement at promoters

应用场景：

创建时间：

2014-08-08

组蛋白变体

染色质转录调控

Eukaryotic nucleosomes consists of an (H3-H4)2 tetramer and two H2A-H2B dimers, around which 147 bp of DNA are wrapped in 1.7 left-handed helical turns. During chromatin assembly, the (H3-H4)2 tetrame

Figshare2016-01-15 更新60

Decoupling of H2Aub and H3K27me3 in early mammalian development

胚胎表观遗传调控

组蛋白修饰解偶联

Polycomb group (PcG) proteins play critical roles during development. H2Aub and H3K27me3 are deposited by Polycomb-repressive Complex 1 and 2 (PRC1/2) respectively, and largely overlap in the genome d

NIAID Data Ecosystem50

Regulation of Budding Yeast CENP-A levels Prevents Misincorporation at Promoter Nucleosomes and Transcriptional Defects

组蛋白变体

染色质结构与转录调控

The exclusive localization of the histone H3 variant CENP-A to centromeres is essential for accurate chromosome segregation. Ubiquitin-mediated proteolysis helps to ensure that CENP-A does not misloca

Figshare2016-09-29 更新40

DNA (de)methylation in embryonic stem cells controls CTCF-dependent chromatin boundaries. DNA (de)methylation in embryonic stem cells controls CTCF-dependent chromatin boundaries

胚胎表观遗传调控

CTCF染色质边界调控

The interplay of DNA (de)methylation and the architectural chromatin protein CTCF is an important regulator of cellular differentiation, but molecular mechanisms determining differential CTCF binding

NIAID Data Ecosystem60

Histone H1 binding is restricted by histone variant H3.3 (FAIRE). Drosophila melanogaster

染色质结构

组蛋白变体

Linker histones are involved in the formation of higher-order chromatin structure. Although linker histones have been implicated in the regulation of specific genes, it still remains unclear what thei

NIAID Data Ecosystem50

A system for genome-wide histone variant dynamics in ES cells reveals dynamic MacroH2A2 replacement at promoters

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