Carbonic anhydrase II in complex with a membrane-impermeant sulfonamide inhibitor
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Carbonic anhydrase II in complex with a membrane-impermeant sulfonamide inhibitor Descriptor: 1-{2-[4-(AMINOSULFONYL)PHENYL]ETHYL}-2,4,6-TRIMETHYLPYRIDINIUM, 4-(HYDROXYMERCURY)BENZOIC ACID, Carbonic anhydrase II, ... Authors: Menchise, V, De Simone, G, Alterio, V, Di Fiore, A, Pedone, C, Scozzafava, A, Supuran, C.T. Deposit date: 2005-04-18 Release date: 2005-10-18 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2 Å) Cite: Carbonic anhydrase inhibitors: stacking with Phe131 determines active site binding region of inhibitors as exemplified by the X-ray crystal structure of a membrane-impermeant antitumor sulfonamide complexed with isozyme II J.Med.Chem., 48, 2005
创建时间：
2005-04-18
