Scenario and workflow of the overall analysis implemented.
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The integrative framework proposed is based on three steps. Step 1 corresponds to the selection of SNPs and CpGs in 1MB window upstream and downstream from each probe in the gene expression array. Step 2 corresponds to the application of LASSO and ENET to each probe obtaining the deviance per probe. Step 3 corresponds to the permutation-based MaxT method application where gene expression levels within the individuals are permuted B = 100 times obtaining the deviance per probe.
创建时间:
2016-02-23



