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The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted host antiviral signaling and translation

NIAID Data Ecosystem2026-03-13 收录

病毒-宿主相互作用

邻近蛋白质组学

数据链接：

https://www.omicsdi.org/dataset/pride/PXD023239 数据链接链接失效反馈

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资源简介：

To study SARS-CoV-2 biology, we generated an atlas of 2422 human proteins vicinal to 17 SARS-CoV-2 viral proteins using proximity proteomics.

应用场景：

创建时间：

2022-02-16

RNA测序分析

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RNA binding protein CPEB1 remodels host and viral RNA landscapes [RNA-Seq]. Homo sapiens

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基因转录调控

In this study, we report that HCMV infection results in widespread alternative splicing (AS), shorter 3′-untranslated regions (3′UTRs) and polyA tail lengthening in host genes and CPEB1 depletion reve

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EP152R-Mediated Endoplasmic Reticulum Stress Contributes to African Swine Fever Virus Infection via the PERK-eIF2a Pathway

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内质网应激

African swine fever virus (ASFV) is a large, icosahedral, double-stranded DNA virus in the Asfarviridae family and the causative agent of African swine fever (ASF). ASFV causes a hemorrhagic fever wit

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Functional interrogation of a SARS-CoV-2 host protein interactome identifies unique and shared coronavirus host factors. Functional interrogation of a SARS-CoV-2 host protein interactome identifies unique and shared coronavirus host factors

冠状病毒宿主因子

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The ongoing SARS-CoV-2 pandemic has devastated the global economy and claimed more than one million lives, presenting an urgent global health crisis. To identify host factors required for infection by

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Ebola and Marburg virus infection in Bat-Immune-System (BIS) mouse model

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In additioIn addition to their beneficial role in ecosystems, bats serve as reservoirs for a diverse range of viruses, including some highly pathogenic to humans, yet they harbor these pathogens witho

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The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted host antiviral signaling and translation

资源简介：

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