The epigenetic modifier Fam208a is required to maintain epiblast cell potency

ChEBI2017-06-01 更新2026-07-12 收录

干细胞多能性调控

表观遗传修饰

数据链接：

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The epigenetic modifier Fam208a is required to maintain epiblast cell potency

创建时间：

2017-06-01

PCGF6, a polycomb group protein, regulates mesodermal lineage differentiation in murine ES cells and functions in iPS reprogramming. Mus musculus

干细胞多能性调控

iPSC重编程

Polycomb group (PcG) proteins comprise a large group of evolutionary conserved factors with essential roles for embryonic development and adult stem cell function. PcG proteins constitute two main mul

NIAID Data Ecosystem140

GO:0070989 (oxidative demethylation)

表观遗传修饰

功能基因网络

This network was assembled automatically by INDRA (http://indra.bio) by processing all available biomedical literature with multiple machine reading systems, and integrating curated pathway databases.

NIAID Data Ecosystem40

ZIC2 and ZIC3 promote SWI/SNF recruitment to safeguard progression towards human primed pluripotency [ChIP-seq]. ZIC2 and ZIC3 promote SWI/SNF recruitment to safeguard progression towards human primed pluripotency [ChIP-seq]

干细胞多能性调控

表观遗传

The primed epiblast acts as a transitional stage between the relatively homogeneous naïve epiblast and the gastrulating embryo. Its formation entails coordinated changes in regulatory circuits driven

NIAID Data Ecosystem00

Crystal structure of the TAL effector dHax3 bound to methylated dsDNA

DNA复合物

表观遗传修饰

Crystal structure of the TAL effector dHax3 bound to methylated dsDNA Descriptor: DNA (5'-D(*AP*GP*GP*GP*AP*GP*GP*TP*AP*GP*AP*GP*GP*GP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*CP*CP*CP*TP*(5CM)P*TP*AP*(5CM)P

Protein Data Bank Japan2023-11-08 更新40

RVD HA specifically contacts 5mC through van der Waals interactions

DNA相互作用

表观遗传修饰

RVD HA specifically contacts 5mC through van der Waals interactions

NIAID Data Ecosystem20